BDBM50664906 CHEMBL6176031

SMILES O=[N+]([O-])c1cc(-c2nnc(CN3CCN(C(c4ccccc4)c4ccc(Cl)cc4)CC3)o2)cc([N+](=O)[O-])c1

InChI Key InChIKey=LUBJBRITORKKGW-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50664906   

TargetProstaglandin G/H synthase 2(Sheep)
India Institute of Technology (Banaras Hindu University)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50664906BDBM50664906(CHEMBL6176031)
Affinity DataIC50: 600nMAssay Description:Inhibition of recombinant ovine COX-2 using arachidonic acid as substrate in presence of hemin by TMPD reagent-based colorimetryMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
India Institute of Technology (Banaras Hindu University)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50664906BDBM50664906(CHEMBL6176031)
Affinity DataIC50: 1.80E+4nMAssay Description:Inhibition of 5-LOX (unknown origin) using arachidonic acid as substrate preincubated for 5 mins followed by substrate addition measured after 10 min...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetProstaglandin G/H synthase 1(Sheep)
India Institute of Technology (Banaras Hindu University)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50664906BDBM50664906(CHEMBL6176031)
Affinity DataIC50: 3.77E+4nMAssay Description:Inhibition of ovine COX-1 using arachidonic acid as substrate in presence of hemin by TMPD reagent-based colorimetryMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed