BDBM50664948 CHEMBL6172848

SMILES Cc1cc2c(cc1C(=O)/C(Br)=C/c1ccc(C(=O)O)cc1)C(C)(C)CCC2(C)C

InChI Key InChIKey=XVVBVBVCMXXDPT-UHFFFAOYSA-N

Data  1 IC50  3 Kd  3 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50664948   

TargetRetinoic acid receptor alpha(Human)
Xiamen University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50664948BDBM50664948(CHEMBL6172848)
Affinity DataEC50:  424nMAssay Description:Agonist activity at Gal4-fused full length human RARalpha LBD transfected in HEK293T cells co-transfected with pG5luc reporter and Renilla-luc assess...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetRetinoic acid receptor alpha(Human)
Xiamen University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50664948BDBM50664948(CHEMBL6172848)
Affinity DataKd:  433nMAssay Description:Binding affinity to N-terminal His-tagged human RARalpha LBD extracted from Escherichia coli BL21 (DE3) cells assessed as dissociation constant by fl...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetRetinoic acid receptor RXR-alpha(Human)
Xiamen University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50664948BDBM50664948(CHEMBL6172848)
Affinity DataIC50: 480nMAssay Description:Partial agonist activity at Gal4-fused full length RXRalpha LBD (unknown origin) transfected in HEK293T cells co-transfected with pG5luc reporter and...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetRetinoic acid receptor RXR-alpha(Human)
Xiamen University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50664948BDBM50664948(CHEMBL6172848)
Affinity DataKd:  663nMAssay Description:Binding affinity to N-terminal His-tagged human RXRalpha LBD extracted from Escherichia coli BL21 (DE3) cells assessed as dissociation constant by fl...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetRetinoic acid receptor alpha(Human)
Xiamen University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50664948BDBM50664948(CHEMBL6172848)
Affinity DataKd:  1.08E+3nMAssay Description:Binding affinity to N-terminal His-tagged human RARalpha LBD extracted from Escherichia coli BL21 (DE3) cells assessed as dissociation constant by IT...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetRetinoic acid receptor gamma(Human)
Xiamen University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50664948BDBM50664948(CHEMBL6172848)
Affinity DataEC50:  2.24E+3nMAssay Description:Agonist activity at Gal4-fused full length human RARgamma LBD transfected in HEK293T cells co-transfected with pG5luc reporter and Renilla-luc assess...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetRetinoic acid receptor RXR-alpha(Human)
Xiamen University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50664948BDBM50664948(CHEMBL6172848)
Affinity DataEC50:  3.52E+3nMAssay Description:Agonist activity at Gal4-fused full length RXRalpha LBD (unknown origin) transfected in HEK293T cells co-transfected with pG5luc reporter and Renilla...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed