BDBM50666171 CHEMBL6173446

SMILES COc1cc(OC)c(Cl)c(-c2ccc3c(/C=C/c4ccc(C(=O)N5CCNCC5)cc4)n[nH]c3c2)c1Cl

InChI Key InChIKey=WHFUFGYNFNBQQP-UHFFFAOYSA-N

Data  10 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 10 hits for monomerid = 50666171   

TargetFibroblast growth factor receptor 1(Human)
Sichuan University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50666171BDBM50666171(CHEMBL6173446)
Affinity DataIC50: 2.30nMAssay Description:Inhibition of human FGFR1 using KKKSPGEYVNIEFG as substrate incubated for 40 mins in presence of [gamma-33P]-ATP by scintillation counter analysisMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetFibroblast growth factor receptor 1(Human)
Sichuan University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50666171BDBM50666171(CHEMBL6173446)
Affinity DataIC50: 2.30nMAssay Description:Inhibition of human FGFR1More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetFibroblast growth factor receptor 2(Human)
Sichuan University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50666171BDBM50666171(CHEMBL6173446)
Affinity DataIC50: 7nMAssay Description:Inhibition of human FGFR2More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetFibroblast growth factor receptor 3(Human)
Sichuan University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50666171BDBM50666171(CHEMBL6173446)
Affinity DataIC50: 11nMAssay Description:Inhibition of human FGFR3More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetTyrosine-protein kinase ABL1(Human)
Sichuan University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50666171BDBM50666171(CHEMBL6173446)
Affinity DataIC50: 26nMAssay Description:Inhibition of human ABL1More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetVascular endothelial growth factor receptor 1(Human)
Sichuan University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50666171BDBM50666171(CHEMBL6173446)
Affinity DataIC50: 61nMAssay Description:Inhibition of human FLT1More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetVascular endothelial growth factor receptor 3(Human)
Sichuan University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50666171BDBM50666171(CHEMBL6173446)
Affinity DataIC50: 112nMAssay Description:Inhibition of human FLT4More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetFibroblast growth factor receptor 4(Human)
Sichuan University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50666171BDBM50666171(CHEMBL6173446)
Affinity DataIC50: 163nMAssay Description:Inhibition of human FGFR4More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
Sichuan University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50666171BDBM50666171(CHEMBL6173446)
Affinity DataIC50: 176nMAssay Description:Inhibition of human KDRMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Human)
Sichuan University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50666171BDBM50666171(CHEMBL6173446)
Affinity DataIC50: 353nMAssay Description:Inhibition of human FLT3More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed