BDBM50666282 CHEMBL6162870

SMILES CCC[C@@H](CO)Nc1nc(N)nc2c3ccccc3n(Cc3cc(CN[C@H]4CCOC4)ccc3OC)c12

InChI Key InChIKey=VXEJIMFZIVVCFP-UHFFFAOYSA-N

Data  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50666282   

TargetToll-like receptor 8(Human)
Bristol Myers Squibb Research & Development

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50666282BDBM50666282(CHEMBL6162870)
Affinity DataEC50:  114nMAssay Description:Agonist activity at TLR8 in HEK-Blue hTLR8 cells coexpressing SEAP reporter transgene assessed as SEAP level incubated for 18 hrs by SEAP reporter ge...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetToll-like receptor 7(Human)
Bristol Myers Squibb Research & Development

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50666282BDBM50666282(CHEMBL6162870)
Affinity DataEC50:  196nMAssay Description:Agonist activity at TLR7 in HEK-Blue hTLR7 cells coexpressing SEAP reporter transgene assessed as SEAP level incubated for 18 hrs by SEAP reporter ge...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed