BDBM50666326 CHEMBL6176298

SMILES C1=C(C(=O)NC(=O)N1[C@H]2[C@H]([C@@H]([C@H](O2)COP(=O)(O)O)O)F)CO

InChI Key InChIKey=MCTFWHKMGAFQIE-UHFFFAOYSA-N

Data  1 IC50  2 Kd

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50666326   

Target2'-deoxynucleoside 5'-phosphate N-hydrolase 1(Human)
Albert Einstein College of Medicine

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50666326BDBM50666326(CHEMBL6176298)
Affinity DataKd:  430nMAssay Description:Binding affinity to wild-type truncated human DNPH1 extracted from Escherichia coli BL21DE3 assessed as dissociation constant by ITC analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMedPDB3D3D Structure (crystal)
Target2'-deoxynucleoside 5'-phosphate N-hydrolase 1(Human)
Albert Einstein College of Medicine

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50666326BDBM50666326(CHEMBL6176298)
Affinity DataKd:  570nMAssay Description:Competitive inhibition of wild-type truncated human DNPH1 extracted from Escherichia coli BL21DE3 using hmdUMP as substrate preincubated for 30 mins ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMedPDB3D3D Structure (crystal)
Target2'-deoxynucleoside 5'-phosphate N-hydrolase 1(Human)
Albert Einstein College of Medicine

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50666326BDBM50666326(CHEMBL6176298)
Affinity DataIC50: 1.50E+3nMAssay Description:Inhibition of wild-type truncated human DNPH1 extracted from Escherichia coli BL21DE3 assessed as decrease in hmdUMP hydrolysis preincubated for 30 m...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMedPDB3D3D Structure (crystal)