BDBM50666545 CHEMBL6168478

SMILES CC(C)CC(C(=O)NO)C(=O)NCCc1c[nH]c2ccc(OCc3ccccc3)cc12

InChI Key InChIKey=XWWJBYTUKGIAIL-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50666545   

TargetLeucyl-cystinyl aminopeptidase(Human)
Univ. Lille

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50666545BDBM50666545(CHEMBL6168478)
Affinity DataIC50: 23nMAssay Description:Inhibition of human recombinant IRAP using L-AMC as substrate preincubated for 30 mins followed by substrate addition and measured after 1 hr by micr...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetEndoplasmic reticulum aminopeptidase 2(Human)
Univ. Lille

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50666545BDBM50666545(CHEMBL6168478)
Affinity DataIC50: 590nMAssay Description:Inhibition of human recombinant ERAP2 using R-AMC as substrate preincubated for 30 mins followed by substrate addition and measured after 1 hr by mic...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetEndoplasmic reticulum aminopeptidase 1(Human)
Univ. Lille

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50666545BDBM50666545(CHEMBL6168478)
Affinity DataIC50: 720nMAssay Description:Inhibition of human recombinant ERAP1 using L-AMC as substrate preincubated for 30 mins followed by substrate addition and measured after 1 hr by mic...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetLeucyl-cystinyl aminopeptidase(Human)
Univ. Lille

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50666545BDBM50666545(CHEMBL6168478)
Affinity DataIC50: 2.91E+3nMAssay Description:Inhibition of IRAP in human HEK293T cells assessed as inhibition of antigen cross presentation by measuring IL-6 production incubated for 17 to 19 hr...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed