BDBM50666567 CHEMBL6169943

SMILES CC(C)CC(C(=O)NO)C(=O)N[C@@H](Cc1c[nH]c2ccc(OCc3ccccc3)cc12)C(N)=O

InChI Key InChIKey=FIYNVGNMDVLTLB-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50666567   

TargetLeucyl-cystinyl aminopeptidase(Human)
Univ. Lille

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50666567BDBM50666567(CHEMBL6169943)
Affinity DataIC50: 3nMAssay Description:Inhibition of human recombinant IRAP using L-AMC as substrate preincubated for 30 mins followed by substrate addition and measured after 1 hr by micr...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetEndoplasmic reticulum aminopeptidase 1(Human)
Univ. Lille

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50666567BDBM50666567(CHEMBL6169943)
Affinity DataIC50: 460nMAssay Description:Inhibition of human recombinant ERAP1 using L-AMC as substrate preincubated for 30 mins followed by substrate addition and measured after 1 hr by mic...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetEndoplasmic reticulum aminopeptidase 2(Human)
Univ. Lille

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50666567BDBM50666567(CHEMBL6169943)
Affinity DataIC50: 4.20E+3nMAssay Description:Inhibition of human recombinant ERAP2 using R-AMC as substrate preincubated for 30 mins followed by substrate addition and measured after 1 hr by mic...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetLeucyl-cystinyl aminopeptidase(Human)
Univ. Lille

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50666567BDBM50666567(CHEMBL6169943)
Affinity DataIC50: 1.47E+4nMAssay Description:Inhibition of IRAP in human HEK293T cells assessed as inhibition of antigen cross presentation by measuring IL-6 production incubated for 17 to 19 hr...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed