BDBM50666803 CHEMBL6167743

SMILES C[C@@H](C(=O)Nc1cccc(OC2CCN(C(=O)CN3CCC(N4CCN(c5ccc6c(c5)C(=O)N(C5CCC(=O)NC5=O)C6=O)CC4)CC3)CC2)c1)[C@H]1CC[C@@H](c2ccnc3ccc(F)cc32)CC1

InChI Key InChIKey=LDFDXTNMCGLUMQ-UHFFFAOYSA-N

Data  2 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50666803   

TargetIndoleamine 2,3-dioxygenase 1(Human)
Northwestern University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50666803BDBM50666803(CHEMBL6167743)
Affinity DataKd:  140nMAssay Description:Binding affinity to 6His-tagged recombinant IDO1 (unknown origin) assessed as dissociation constant by Biolayer Interferometry assayMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetProtein cereblon(Human)
Northwestern University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50666803BDBM50666803(CHEMBL6167743)
Affinity DataKd:  380nMAssay Description:Binding affinity to CRBN (unknown origin) assessed as dissociation constant by Biolayer Interferometry assayMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed