BDBM50666859 CHEMBL6177078

SMILES C=CC(=O)N1CCc2c(nc(N3CCN(C)C(=O)C3)nc2N2CC[C@@H](Nc3ncc(Cl)c(OC)n3)C2)C1

InChI Key InChIKey=AYCMWWFUBMLXBF-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50666859   

TargetCyclin-dependent kinase 12(Human)
Insilico Medicine Shanghai Ltd

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50666859BDBM50666859(CHEMBL6177078)
Affinity DataIC50: 166nMAssay Description:Inhibition of CDK12/Cyclin K (unknown origin) using pS7-CTD peptide and ATP as substrate incubated for 120 mins by ADP-Glo reagent based luminescence...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed