BDBM50666896 CHEMBL6175158

SMILES O=C(Nc1cc(C(F)(F)F)cc(C(F)(F)F)c1)N[C@@H](Cc1ccccc1)Cn1c[n+](Cc2ccc3ccccc3c2)c2ccccc21

InChI Key InChIKey=WPUWQYHTCVPBGI-UHFFFAOYSA-O

Data  3 IC50  2 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50666896   

TargetMitogen-activated protein kinase 3(Human)
Henan Normal University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50666896BDBM50666896(CHEMBL6175158)
Affinity DataIC50: 92nMAssay Description:Inhibition of ERK1 (unknown origin) incubated for 60 mins by luminescence based ADP-Glo kinase assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetMitogen-activated protein kinase 1(Human)
Henan Normal University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50666896BDBM50666896(CHEMBL6175158)
Affinity DataIC50: 98nMAssay Description:Inhibition of ERK2 (unknown origin) incubated for 60 mins by luminescence based ADP-Glo kinase assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetMitogen-activated protein kinase 1(Human)
Henan Normal University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50666896BDBM50666896(CHEMBL6175158)
Affinity DataKd:  116nMAssay Description:Binding affinity to ERK2 (unknown origin) assessed as dissociation constant by MST analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetMitogen-activated protein kinase 3(Human)
Henan Normal University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50666896BDBM50666896(CHEMBL6175158)
Affinity DataKd:  159nMAssay Description:Binding affinity to ERK1 (unknown origin) assessed as dissociation constant by MST analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetRibosomal protein S6 kinase alpha-1(Human)
Henan Normal University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50666896BDBM50666896(CHEMBL6175158)
Affinity DataIC50: 674nMAssay Description:Inhibition of RSK1 (unknown origin) incubated for 60 mins by luminescence based ADP-Glo kinase assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed