BDBM50667009 CHEMBL6177245

SMILES CC[C@@H]1C(=O)N(C)c2cnc(Nc3cc(N4CCNCC4)ccc3OCCO)nc2N1C1CCCC1

InChI Key InChIKey=DLWIMTTYEPBARF-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50667009   

TargetSerine/threonine-protein kinase PLK1(Human)
Hefei University of Technology

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50667009BDBM50667009(CHEMBL6177245)
Affinity DataIC50: 39nMAssay Description:Inhibition of human PLK1 using ATF2 as substrate incubated for 40 mins in presence of [gamma-33P]ATP/Mg acetate by scintillation counting analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetSerine/threonine-protein kinase PLK3(Human)
Hefei University of Technology

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50667009BDBM50667009(CHEMBL6177245)
Affinity DataIC50: 5.83E+3nMAssay Description:Inhibition of human PLK3 using ATF2 as substrate incubated for 40 mins in presence of [gamma-33P]ATP/Mg acetate by scintillation counting analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetSerine/threonine-protein kinase PLK2(Human)
Hefei University of Technology

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50667009BDBM50667009(CHEMBL6177245)
Affinity DataIC50: 1.01E+4nMAssay Description:Inhibition of human PLK2 using ATF2 as substrate incubated for 40 mins in presence of [gamma-33P]ATP/Mg acetate by scintillation counting analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed