BDBM50667368 CHEMBL6189220

SMILES CCC(CC)(c1ccc(C(=O)NCCCCC(=O)NO)cc1)c1ccc(OCC(O)C(C)(C)C)c(C)n1

InChI Key InChIKey=BTEXLTFGTVAWMQ-UHFFFAOYSA-N

Data  10 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 10 hits for monomerid = 50667368   

TargetPolyamine deacetylase HDAC10(Human)
McGill University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50667368BDBM50667368(CHEMBL6189220)
Affinity DataIC50: 1.40nMAssay Description:Inhibition of human HDAC10 using Ac-spermidine-AMC as substrate by fluorogenic assayMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetHistone deacetylase 11(Human)
McGill University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50667368BDBM50667368(CHEMBL6189220)
Affinity DataIC50: 2nMAssay Description:Inhibition of human HDAC11 using Boc-Lys(trifluoroacetyl)-AMC as substrate by fluorogenic assayMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetHistone deacetylase 1(Human)
McGill University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50667368BDBM50667368(CHEMBL6189220)
Affinity DataIC50: 2.5nMAssay Description:Inhibition of human HDAC1 using RHKK(Ac)AMC as substrate by fluorogenic assayMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetHistone deacetylase 8(Human)
McGill University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50667368BDBM50667368(CHEMBL6189220)
Affinity DataIC50: 3.30nMAssay Description:Inhibition of human HDAC8 using RHK(Ac)K(Ac)-AMC as substrate by fluorogenic assayMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetHistone deacetylase 2(Human)
McGill University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50667368BDBM50667368(CHEMBL6189220)
Affinity DataIC50: 4.60nMAssay Description:Inhibition of human HDAC2 using RHKK(Ac)AMC as substrate by fluorogenic assayMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetHistone deacetylase 7(Human)
McGill University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50667368BDBM50667368(CHEMBL6189220)
Affinity DataIC50: 5.5nMAssay Description:Inhibition of human HDAC7 using Boc-Lys(trifluoroacetyl)-AMC as substrate by fluorogenic assayMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetHistone deacetylase 5(Human)
McGill University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50667368BDBM50667368(CHEMBL6189220)
Affinity DataIC50: 5.90nMAssay Description:Inhibition of human HDAC5 using Boc-Lys(trifluoroacetyl)-AMC as substrate by fluorogenic assayMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetHistone deacetylase 6(Human)
McGill University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50667368BDBM50667368(CHEMBL6189220)
Affinity DataIC50: 6.30nMAssay Description:Inhibition of human HDAC6 using RHKK(Ac)AMC as substrate by fluorogenic assayMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetHistone deacetylase 4(Human)
McGill University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50667368BDBM50667368(CHEMBL6189220)
Affinity DataIC50: 6.80nMAssay Description:Inhibition of human HDAC4 using Boc-Lys(trifluoroacetyl)-AMC as substrate by fluorogenic assayMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetHistone deacetylase 3(Human)
McGill University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50667368BDBM50667368(CHEMBL6189220)
Affinity DataIC50: 10nMAssay Description:Inhibition of human HDAC3 using RHKK(Ac)AMC as substrate by fluorogenic assayMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed