BDBM50667986 CHEMBL6192383

SMILES O=C(C1CCN(c2nccc(N3CCC4(CC4)C3=O)n2)CC1)N1OCC[C@H]1c1cncc(F)c1

InChI Key InChIKey=SJPUUWUONRNPJH-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50667986   

TargetReceptor-interacting serine/threonine-protein kinase 1(Human)
Smith, Gambrell & Russell

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50667986BDBM50667986(CHEMBL6192383)
Affinity DataIC50: 0.0100nMAssay Description:Inhibition of recombinant human RIPK1 (1 to 375 residues) preincubated for 30 mins followed by ATP addition measured after 240 mins by ADP Glo assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed