BDBM50668700 CHEMBL6188381

SMILES CCC1CN2CCNCc3ccc(C(=O)NCCF)c1c32

InChI Key InChIKey=DYQUMJMWSSVIHQ-UHFFFAOYSA-N

Data  3 KI  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50668700   

Target5-hydroxytryptamine receptor 2C(Human)
Arena Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50668700BDBM50668700(CHEMBL6188381)
Affinity DataEC50:  80nMAssay Description:Displacement of [125I]-DOI from 5-HT2C receptor (unknown origin) expressed in HEK293 cell membrane incubated for 1 hr by scintillation counter analys...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
Target5-hydroxytryptamine receptor 2C(Human)
Arena Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50668700BDBM50668700(CHEMBL6188381)
Affinity DataKi:  121nMAssay Description:Displacement of [125I]-DOI from 5-HT2C receptor (unknown origin) expressed in HEK293 cell membrane assessed as inhibition constant incubated for 1 hr...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
Target5-hydroxytryptamine receptor 2A(Human)
Arena Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50668700BDBM50668700(CHEMBL6188381)
Affinity DataKi:  212nMAssay Description:Displacement of [125I]-DOI from 5-HT2A receptor (unknown origin) expressed in HEK293 cell membrane assessed as inhibition constant incubated for 1 hr...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
Target5-hydroxytryptamine receptor 2B(Human)
Arena Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50668700BDBM50668700(CHEMBL6188381)
Affinity DataKi: >5.00E+4nMAssay Description:Displacement of [125I]-DOI from 5-HT2B receptor (unknown origin) expressed in HEK293 cell membrane assessed as inhibition constant incubated for 1 hr...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed