BDBM50668924 CHEMBL6190558

SMILES Cc1ccc(c(c1)F)CC(=O)N2CC[C@@H]([C@@H](C2)C(=O)N[C@H](CC3CCCCC3)C(=O)N(C)C)NC(=O)CCN4c5ccccc5NC4=O

InChI Key InChIKey=BTOHHWKNNMWWQD-UHFFFAOYSA-N

Data  1 IC50  1 Kd

PDB links: 1 PDB ID matches this monomer.

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50668924   

LigandChemical structure of BindingDB Monomer ID 50668924BDBM50668924(CHEMBL6190558)
Affinity DataIC50: 17nMAssay Description:Inhibition of full-length human WRN extracted from baculovirus infected Sf9 cells using TTTTTTTTTTTTTTTTTTTTTTCCAAGTAAAACGACGGCCAGTGC(BHQ) and (Cyani...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMedPDB3D3D Structure (crystal)
LigandChemical structure of BindingDB Monomer ID 50668924BDBM50668924(CHEMBL6190558)
Affinity DataKd:  86nMAssay Description:Binding affinity to biotin-Tris NTA-neutravidin surface-immobilized C-terminal His-tagged human WRN (506 to 1068 residues) extracted from baculovirus...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMedPDB3D3D Structure (crystal)