BDBM50668925 CHEMBL6193169

SMILES CN(C)C(=O)[C@@H](CC1CCCCC1)NC(=O)[C@@H]1CN(C(=O)Cc2ccc(C(F)(F)F)cc2F)CC[C@@H]1NC(=O)CCn1c(=O)[nH]c2cc(CC(C)(C)O)ccc21

InChI Key InChIKey=QDGFGVIPBGNRJG-UHFFFAOYSA-N

Data  1 IC50  1 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50668925   

LigandChemical structure of BindingDB Monomer ID 50668925BDBM50668925(CHEMBL6193169)
Affinity DataKd:  1.90nMAssay Description:Binding affinity to biotin-Tris NTA-neutravidin surface-immobilized C-terminal His-tagged human WRN (506 to 1068 residues) extracted from baculovirus...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
LigandChemical structure of BindingDB Monomer ID 50668925BDBM50668925(CHEMBL6193169)
Affinity DataIC50: 4nMAssay Description:Inhibition of full-length human WRN extracted from baculovirus infected Sf9 cells using TTTTTTTTTTTTTTTTTTTTTTCCAAGTAAAACGACGGCCAGTGC(BHQ) and (Cyani...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed