BDBM50668965 CHEMBL6191148

SMILES CNC(=O)[C@@H](CC1CCCCC1)NC(=O)C1CN(C(=O)Cc2ccc(C)cc2F)CCC1NC(=O)CCn1c(=O)[nH]c2ccccc21

InChI Key InChIKey=NOWPDCNKNCJAIP-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50668965   

LigandChemical structure of BindingDB Monomer ID 50668965BDBM50668965(CHEMBL6191148)
Affinity DataIC50: 0.228nMAssay Description:Inhibition of full-length human WRN extracted from baculovirus infected Sf9 cells using TTTTTTTTTTTTTTTTTTTTTTCCAAGTAAAACGACGGCCAGTGC(BHQ) and (Cyani...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed
TargetRecQ-like DNA helicase BLM(Human)
Abbvie

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50668965BDBM50668965(CHEMBL6191148)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of BLM (unknown origin) using TTTTTTTTTTTTTTTTTTTTTTCCAAGTAAAACGACGGCCAGTGC(BHQ) and (Cyanine5)GCACTGGCCGTCGTTTTACGGTCGTGACT as dsDNA subs...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/6/2026
Entry Details
PubMed