BDBM506725 US12534458, Example 4

SMILES NS(=O)(=O)N1CCC2(CC1)[C@H](c1nccc(-c3ccccc3)n1)C2(F)F

InChI Key InChIKey=FKNINAMMTDGYKM-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 506725   

TargetNeuronal acetylcholine receptor subunit alpha-7(Human)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 506725BDBM506725(US12534458, Example 4)
Affinity DataEC50:  1.90E+3nMAssay Description:mGluR5 activity was determined in a cell-based assay.More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/8/2026
Entry Details
US Patent