BDBM506731 US12534458, Example B1

SMILES NS(=O)(=O)N1CCC2(CC1)[C@@H](c1cccc(-c3ccc(C(F)(F)F)cc3)n1)C2(F)F

InChI Key InChIKey=WOVAADHSJMPEGN-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 506731   

TargetNeuronal acetylcholine receptor subunit alpha-7(Human)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 506731BDBM506731(US12534458, Example B1)
Affinity DataEC50:  4.40E+3nMAssay Description:mGluR5 activity was determined in a cell-based assay.More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/8/2026
Entry Details
US Patent