BDBM506846 US11046658, Example 1::US20250388553, Example 1

SMILES Cc1ccc(cc1-c1cnc(N)c(n1)C(=O)NCC(C)(C)O)C(O)(C(N)=O)C(F)(F)F

InChI Key InChIKey=DVRSFYPTVOWAFS-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 506846   

LigandChemical structure of BindingDB Monomer ID 506846BDBM506846(US11046658, Example 1 | US20250388553, Example 1)
Affinity DataIC50: 100nMAssay Description:Keywords: apoptosis, BH3 domain, Bcl2-A1, BIM, caspase, cancer Primary Collaborator: Todd Golub, Broad Institute, golub@broadinstitute.org Assay Over...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/6/2026
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 506846BDBM506846(US11046658, Example 1 | US20250388553, Example 1)
Affinity DataIC50: 100nMAssay Description:Keywords: apoptosis, BH3 domain, Bcl2-A1, BIM, caspase, cancer Primary Collaborator: Todd Golub, Broad Institute, golub@broadinstitute.org Assay Over...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/6/2026
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 506846BDBM506846(US11046658, Example 1 | US20250388553, Example 1)
Affinity DataIC50: 100nMAssay Description:Materials: [γ-33P]ATP (10 mCi/mL) and Wheat Germ Agglutinin (WGA) YSi SPA Scintillation Beads was purchased from Perkin Elmer (Waltham, Mass.). ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2021
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 506846BDBM506846(US11046658, Example 1 | US20250388553, Example 1)
Affinity DataIC50: 100nMAssay Description:Materials: [γ-33P]ATP (10 mCi/mL) and Wheat Germ Agglutinin (WGA) YSi SPA Scintillation Beads was purchased from Perkin Elmer (Waltham, Mass.). ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2021
Entry Details
US Patent