BDBM508500 5-chloro-2-methoxy-N-[(8S,9aR)-8-methoxy-5-oxo-8,9,9a,10-tetrahydro-5H,7H-pyrido[3,2-f]pyrrolo[2,1-c][1,4]oxazepin-3-yl]benzenesulfonamide::US11046710, Example 46

SMILES CO[C@H]1C[C@@H]2COc3ncc(NS(=O)(=O)c4cc(Cl)ccc4OC)cc3C(=O)N2C1

InChI Key InChIKey=IRUOBWUTRGYJQC-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 508500   

TargetAlkaline phosphatase, tissue-nonspecific isozyme(Human)
Daiichi Sankyo

US Patent
LigandPNGBDBM508500(5-chloro-2-methoxy-N-[(8S,9aR)-8-methoxy-5-oxo-8,9...)
Affinity DataIC50: 0.5nMAssay Description:COS1 cells (DS Pharma Biomedical Co., Ltd.) were transfected with human TNAP (OriGene Technologies, Inc.) using Lipofectamine LTX & Plus reagent (Inv...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/28/2021
Entry Details
US Patent