BDBM508507 5-chloro-N-[(8S,9aS)-8-hydroxy-7-oxo-8,9,9a,10-tetrahydro-5H,7H-pyrido[3,2-f]pyrrolo[2,1-c][1,4]oxazepin-3-yl]-2-(trifluoromethoxy)benzenesulfonamide::US11046710, Example 56

SMILES O[C@H]1C[C@H]2COc3ncc(NS(=O)(=O)c4cc(Cl)ccc4OC(F)(F)F)cc3CN2C1=O

InChI Key InChIKey=YNEIGHJVQDRXGQ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 508507   

TargetAlkaline phosphatase, tissue-nonspecific isozyme(Human)
Daiichi Sankyo

US Patent
LigandPNGBDBM508507(5-chloro-N-[(8S,9aS)-8-hydroxy-7-oxo-8,9,9a,10-tet...)
Affinity DataIC50: 1.40nMAssay Description:COS1 cells (DS Pharma Biomedical Co., Ltd.) were transfected with human TNAP (OriGene Technologies, Inc.) using Lipofectamine LTX & Plus reagent (Inv...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/28/2021
Entry Details
US Patent