BDBM508893 US11071730, Example 8

SMILES CC(C)n1cnc2cc(nc(Nc3ccncc3F)c12)-c1ccc2c(c1)N([C@@H]1C[C@@H](C1)N1C[C@H](C)[C@H](C)C1)C(=O)C21CCN(CC1)C(=O)C1(C)COC1

InChI Key InChIKey=ZMGSQAUBBOGIAO-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 508893   

TargetMitogen-activated protein kinase kinase kinase kinase 1(Human)
Gilead Sciences

US Patent
LigandPNGBDBM508893(US11071730, Example 8)
Affinity DataIC50: 0.200nMAssay Description:Recombinant HPK1 kinase domain produced via baculovirus infection of insect cells was obtained from Proteros (Proteros Biostructures #PR-0322) and wa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/7/2022
Entry Details
US Patent