BDBM508908 US11071730, Example 20A

SMILES CC(C)n1cnc2cc(nc(Nc3ccncc3F)c12)-c1ccc2c(c1)N([C@@H]1C[C@@H](C1)N1CCC(C)(C)C1)C(=O)C21CCN(CC1)C(=O)[C@H]1CC[C@@H](C)O1

InChI Key InChIKey=RRONVZWPVUGRIA-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 508908   

TargetMitogen-activated protein kinase kinase kinase kinase 1(Human)
Gilead Sciences

US Patent
LigandPNGBDBM508908(US11071730, Example 20A)
Affinity DataIC50: 0.100nMAssay Description:Recombinant HPK1 kinase domain produced via baculovirus infection of insect cells was obtained from Proteros (Proteros Biostructures #PR-0322) and wa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/7/2022
Entry Details
US Patent

TargetMitogen-activated protein kinase kinase kinase kinase 1(Human)
Gilead Sciences

US Patent
LigandPNGBDBM508908(US11071730, Example 20A)
Affinity DataIC50: 0.200nMAssay Description:Recombinant HPK1 kinase domain produced via baculovirus infection of insect cells was obtained from Proteros (Proteros Biostructures #PR-0322) and wa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/7/2022
Entry Details
US Patent