BDBM509011 US11071730, Example 118::US11071730, Example 119

SMILES CC(C)[C@H](O)C(=O)N1CCC2(CC1)C(=O)N(C1CC(C1)N1CCC(C)(C)C1)c1cc(ccc21)-c1cc2ncn(C(C)C)c2c(Nc2ccncc2F)n1

InChI Key InChIKey=GNUUEDKYULTUDX-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 509011   

TargetMitogen-activated protein kinase kinase kinase kinase 1(Human)
Gilead Sciences

US Patent
LigandPNGBDBM509011(US11071730, Example 118 | US11071730, Example 119)
Affinity DataIC50: 0.200nMAssay Description:Recombinant HPK1 kinase domain produced via baculovirus infection of insect cells was obtained from Proteros (Proteros Biostructures #PR-0322) and wa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/7/2022
Entry Details
US Patent

TargetMitogen-activated protein kinase kinase kinase kinase 1(Human)
Gilead Sciences

US Patent
LigandPNGBDBM509011(US11071730, Example 118 | US11071730, Example 119)
Affinity DataIC50: 0.200nMAssay Description:Recombinant HPK1 kinase domain produced via baculovirus infection of insect cells was obtained from Proteros (Proteros Biostructures #PR-0322) and wa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/7/2022
Entry Details
US Patent