BDBM509111 N-{(2S)-2-Amino-4-[{(1R)-1-[1-benzyl-4-(2,5-difluorophenyl)-1H-pyrrol-2-yl]-2,2-dimethylpropyl}(glycoloyl)amino]butanoyl}-beta-alanyl-D-glutamic acid-trifluoroacetic acid::US11071788, Example M24::US12059472, Example M3

SMILES CC(C)(C)[C@@H](N(CC[C@H](N)C(=O)NCCC(=O)N[C@H](CCC(O)=O)C(O)=O)C(=O)CO)c1cc(cn1Cc1ccccc1)-c1cc(F)ccc1F

InChI Key InChIKey=IPQGHUWDCQTNBL-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 509111   

TargetKinesin-like protein KIF11(Human)
Bayer Aktiengesellschaft

US Patent
LigandPNGBDBM509111(US11071788, Example M24 | N-{(2S)-2-Amino-4-[{(1R)...)
Affinity DataIC50: 1.59nMAssay Description:The motor domain of the human kinesin spindle protein KSP/Eg5 (tebu-bio/Cytoskeleton Inc, No. 027EG01-XL) was incubated in a concentration of 10 nM w...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/2/2024
Entry Details
US Patent

TargetKinesin-like protein KIF11(Human)
Bayer Aktiengesellschaft

US Patent
LigandPNGBDBM509111(US11071788, Example M24 | N-{(2S)-2-Amino-4-[{(1R)...)
Affinity DataIC50: 2.90nMAssay Description:The motor domain of the human kinesin spindle protein KSP/Eg5 (tebu-bio/Cytoskeleton Inc, No. 027EG01-XL) was incubated in a concentration of 10 nM w...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/7/2022
Entry Details
US Patent