BDBM509940 US11124497, Compound 591 (Isomer 2)::US11312704, Compound 591 Isomer 2::US11472793, Compound 591 (Isomer 1)::US11524940, Compound 591 (Isomer 2)

SMILES Cc1ccn([C@H](CC2CC2)C(=O)N[C@@H](C[C@@H]2CCNC2=O)C#N)c(=O)c1NC(=O)OC(C)(C)C

InChI Key InChIKey=UJKKNTZPFVPSSL-UHFFFAOYSA-N

Data  7 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 509940   

TargetReplicase polyprotein 1ab(2019-nCoV)
Pardes Biosciences

US Patent
LigandPNGBDBM509940(US11124497, Compound 591 (Isomer 2) | US11524940, ...)
Affinity DataIC50: 6.00E+3nMAssay Description:Compounds were assayed using standard methods to assess compound activity and IC50. As an exemplary for assessment of the SARS-COV2 Mpro, the C-His6-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/6/2022
Entry Details
US Patent

TargetReplicase polyprotein 1ab(2019-nCoV)
Pardes Biosciences

US Patent
LigandPNGBDBM509940(US11124497, Compound 591 (Isomer 2) | US11524940, ...)
Affinity DataIC50: 6.00E+3nMAssay Description:Compounds were assayed using standard methods to assess compound activity and IC50. As an exemplary for assessment of the SARS-COV2 Mpro, the C-His6-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/13/2022
Entry Details
US Patent

TargetReplicase polyprotein 1a(SARS-CoV)
Pardes Biosciences

US Patent
LigandPNGBDBM509940(US11124497, Compound 591 (Isomer 2) | US11524940, ...)
Affinity DataIC50: 6.00E+3nMAssay Description:Compounds are assayed using standard methods to assess compound activity and IC50. As an exemplary for assessment of the SARS-COV2 Mpro, the C-His6-t...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/12/2023
Entry Details
US Patent

TargetReplicase polyprotein 1ab(HCoV-229E)
Pardes Biosciences

US Patent
LigandPNGBDBM509940(US11124497, Compound 591 (Isomer 2) | US11524940, ...)
Affinity DataIC50: 3.00E+4nMAssay Description:Compounds were assayed using standard methods against multiple coronaviral strains, including HCoV 229E and OC43 strains. The antiviral activity of c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/24/2022
Entry Details
US Patent

TargetReplicase polyprotein 1ab(HCoV-229E)
Pardes Biosciences

US Patent
LigandPNGBDBM509940(US11124497, Compound 591 (Isomer 2) | US11524940, ...)
Affinity DataIC50: 3.00E+4nMAssay Description:Compounds were assayed using standard methods against multiple coronaviral strains, including HCoV 229E and OC43 strains. The antiviral activity of c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/6/2022
Entry Details
US Patent

TargetReplicase polyprotein 1ab(HCoV-229E)
Pardes Biosciences

US Patent
LigandPNGBDBM509940(US11124497, Compound 591 (Isomer 2) | US11524940, ...)
Affinity DataIC50: 3.00E+4nMAssay Description:Compounds were assayed using standard methods to assess compound activity and IC50. As an exemplary for assessment of the SARS-COV2 Mpro, the C-His6-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/13/2022
Entry Details
US Patent

TargetReplicase polyprotein 1ab(2019-nCoV)
Pardes Biosciences

US Patent
LigandPNGBDBM509940(US11124497, Compound 591 (Isomer 2) | US11524940, ...)
Affinity DataIC50: 3.00E+4nMAssay Description:Compounds were assayed using standard methods to assess compound activity and IC50. As an exemplary for assessment of the SARS-COV2 Mpro, the C-His6-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/24/2022
Entry Details
US Patent