BDBM5105 1,2,4-Oxadiazole Analogue 15b::4-[(2S)-2-{[(1S)-1-{3-[(3,4-dichlorophenyl)methyl]-1,2,4-oxadiazol-5-yl}-2-hydroxyethyl]carbamoyl}-2-(1-phenylacetamido)ethyl]phenoxyphosphonic acid

SMILES OC[C@H](NC(=O)[C@H](Cc1ccc(OP(O)(O)=O)cc1)NC(=O)Cc1ccccc1)c1nc(Cc2ccc(Cl)c(Cl)c2)no1

InChI Key InChIKey=OBKJDPLCBADFLQ-ZEQRLZLVSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 5105   

TargetTyrosine-protein kinase ZAP-70(Human)
Ariad Pharmaceuticals

LigandPNGBDBM5105(1,2,4-Oxadiazole Analogue 15b | 4-[(2S)-2-{[(1S)-1...)
Affinity DataIC50:  2.00E+3nMAssay Description:Fluorescence polarization competitive binding assays were used to measure the IC50s of compounds binding to the different SH2 domains. The difference...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetGrowth factor receptor-bound protein 2(Human)
Ariad Pharmaceuticals

LigandPNGBDBM5105(1,2,4-Oxadiazole Analogue 15b | 4-[(2S)-2-{[(1S)-1...)
Affinity DataIC50:  2.63E+5nMAssay Description:Fluorescence polarization competitive binding assays were used to measure the IC50s of compounds binding to the different SH2 domains. The difference...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetProto-oncogene tyrosine-protein kinase Src(Human)
Ariad Pharmaceuticals

LigandPNGBDBM5105(1,2,4-Oxadiazole Analogue 15b | 4-[(2S)-2-{[(1S)-1...)
Affinity DataIC50:  3.50E+4nMAssay Description:Fluorescence polarization competitive binding assays were used to measure the IC50s of compounds binding to the different SH2 domains. The difference...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed