BDBM510634 US11078186, Example 88

SMILES CCS(=O)(=O)c1ccc(CC(=O)N2C[C@H](c3ccc(cc3)C(O)(C(F)(F)F)C(F)(F)F)[C@@](C)(C2)c2ccccc2)cc1

InChI Key InChIKey=IOXVMIOBUKRVKC-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 510634   

TargetNuclear receptor ROR-gamma [262-507](Human)
Bristol-Myers Squibb

US Patent
LigandPNGBDBM510634(US11078186, Example 88)
Affinity DataIC50: 72nMAssay Description:The binding of potential ligands to RORγ is measured by competition with [3H]25-hydroxycholesterol (Perkin Elmer NET674250UC) using a scintillat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/16/2022
Entry Details
US Patent