BDBM510831 US11078197, Example 8::US11673886, Example 8

SMILES CC(C)(O)COc1ccc2c(cnn2c1C1CC1)C(=O)N[C@H]1C[C@@]2(C1)CC(C2)Oc1nc2NCCCc2cc1C(N)=O

InChI Key InChIKey=KZSCWGUNPYILBL-PGCLNDTKSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 510831   

TargetRho-associated protein kinase 2(Human)
Bristol-Myers Squibb

US Patent
LigandPNGBDBM510831(US11078197, Example 8 | US11673886, Example 8)
Affinity DataIC50:  5.40nMAssay Description:The effectiveness of compounds of the present invention as ROCK inhibitors can be determined in a 30 μL assay containing 20 mM HEPES, pH 7.5, 20...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent

TargetRho-associated protein kinase 2(Human)
Bristol-Myers Squibb

US Patent
LigandPNGBDBM510831(US11078197, Example 8 | US11673886, Example 8)
Affinity DataIC50:  5.40E+3nMAssay Description:The effectiveness of compounds of the present invention as ROCK inhibitors can be determined in a 30 μL assay containing 20 mM HEPES, pH 7.5, 20...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent