BDBM5111 N-(5-Ethyl-3,4-dimethyl-1,3-thiazol-2(3H)-ylidene)-3-nitrobenzenesulfonamide::N-[(2Z)-5-ethyl-3,4-dimethyl-2,3-dihydro-1,3-thiazol-2-ylidene]-3-nitrobenzene-1-sulfonamide::thiazolidenebenzenesulfonamide deriv. 17d
SMILES CCc1s\c(=N/S(=O)(=O)c2cccc(c2)[N+]([O-])=O)n(C)c1C
InChI Key InChIKey=ZBJKALKLXJZRRE-YPKPFQOOSA-N
Data 4 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 5111
TargetGag-Pol polyprotein [588-1027]/[588-1147](Human immunodeficiency virus type 1)
Yamanouchi Pharmaceutical
Yamanouchi Pharmaceutical
Affinity DataIC50: 850nMpH: 8.4 T: 37°CAssay Description:The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro.More data for this Ligand-Target Pair
TargetReverse transcriptase protein(Human immunodeficiency virus type 1)
Korea Institute of Science and Technology
Curated by ChEMBL
Korea Institute of Science and Technology
Curated by ChEMBL
Affinity DataIC50: 6.31E+3nMAssay Description:Inhibition of HIV1 reverse transcriptase K103N mutant by HeLa-MAGI assayMore data for this Ligand-Target Pair
TargetGag-Pol polyprotein [588-1127,Y768C]/[588-1147,Y768C](Human immunodeficiency virus type 1)
Yamanouchi Pharmaceutical
Yamanouchi Pharmaceutical
Affinity DataIC50: 470nMpH: 8.4 T: 37°CAssay Description:The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro.More data for this Ligand-Target Pair
TargetGag-Pol polyprotein [588-1027,K690N]/[588-1147,K690N](Human immunodeficiency virus type 1)
Yamanouchi Pharmaceutical
Yamanouchi Pharmaceutical
Affinity DataIC50: 6.30E+3nMpH: 8.4 T: 37°CAssay Description:The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro.More data for this Ligand-Target Pair