BDBM511445 US11059784, Example 54

SMILES COc1cccc(c1)C(\C)=N\OCc1ccc(cc1)[C@H]1CC[C@](N)(COP(O)(O)=O)C1

InChI Key InChIKey=AYEZVYVDAYPMDR-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 511445   

TargetSphingosine 1-phosphate receptor 1(Human)
Bristol-Myers Squibb

US Patent
LigandPNGBDBM511445(US11059784, Example 54)
Affinity DataIC50: 14.2nMAssay Description:Membranes were prepared from CHO cells expressing human S1P1. Cells pellets (1×109 cells/pellet) were suspended in buffer containing 20 mM HEPES (4-(...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/23/2022
Entry Details
US Patent