BDBM511528 3-fluoro-4-piperidin-4- ylsulfanylbenzenesulfonamide hydrochloride (intermediate 8)/ 3-[2-[(5-methyltetrazol-2- yl)methyl]-4-(trifluoromethyl)- phenyl]propanoic acid (CAS- RN 1646783-83-6)::US11059794, Example 5.01::US11059794, Example 7.00::US11059794, Example 8.00
SMILES Cc1nnn(Cc2cc(ccc2CCC(=O)N2CCC(CC2)Sc2ccc(cc2F)S(N)(=O)=O)C(F)(F)F)n1
InChI Key InChIKey=RJDGGCMPSZYTGD-UHFFFAOYSA-N
Data 4 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 511528
Affinity DataIC50: 4nMAssay Description:ATX inhibition was measured by a fluorescence quenching assay using a specifically labeled substrate analogue (MR121 substrate). To obtain this MR121...More data for this Ligand-Target Pair
Affinity DataIC50: 5nMAssay Description:ATX inhibition was measured by a fluorescence quenching assay using a specifically labeled substrate analogue (MR121 substrate). To obtain this MR121...More data for this Ligand-Target Pair
Affinity DataIC50: 3nMAssay Description:ATX inhibition was measured by a fluorescence quenching assay using a specifically labeled substrate analogue (MR121 substrate). To obtain this MR121...More data for this Ligand-Target Pair
Affinity DataIC50: 20.7nMAssay Description:Human carbonic anhydrase II (hCA-II) inhibition was measured by an absorbance method using 4-nitrophenyl acetate (4-NPA) as its substrate. 4-NPA can ...More data for this Ligand-Target Pair