BDBM511530 4-(piperidin-4- ylmethyl)benzenesulfonamide hydrochloride (CAS-RN 333986-77-9)/2-cyclopropyl- 6-(oxan-4-ylmethoxy)pyridine- 4-carboxylic acid (CAS-RN 1810776-23-8)::US11059794, Example 5.03

SMILES NS(=O)(=O)c1ccc(CC2CCN(CC2)C(=O)c2cc(OCC3CCOCC3)nc(c2)C2CC2)cc1

InChI Key InChIKey=NDONGBDLTYRPQB-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 511530   

TargetCarbonic anhydrase 2(Homo sapiens (Human))
Hoffmann-La Roche

US Patent
LigandPNGBDBM511530(4-(piperidin-4- ylmethyl)benzenesulfonamide hydroc...)
Affinity DataIC50:  109nMAssay Description:Human carbonic anhydrase II (hCA-II) inhibition was measured by an absorbance method using 4-nitrophenyl acetate (4-NPA) as its substrate. 4-NPA can ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAtaxin-1(Homo sapiens (Human))
Hoffmann-La Roche

US Patent
LigandPNGBDBM511530(4-(piperidin-4- ylmethyl)benzenesulfonamide hydroc...)
Affinity DataIC50:  1nMAssay Description:ATX inhibition was measured by a fluorescence quenching assay using a specifically labeled substrate analogue (MR121 substrate). To obtain this MR121...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent