BDBM511719 (3S)-2-(2-(3-acetyl-5-(2- methylpyrimidin-5-yl)-1H-indazol-1- yl)acetyl)-N-(6-bromo-3-methylpyridin-2- yl)-5-((4-methylpiperazin-1-yl)methyl)-2- azabicyclo[3.1.0]hexane-3-carboxamide::US11084800, Cpd No. 24::US11708351, Compound 24

SMILES CN1CCN(CC23CC2N([C@@H](C3)C(=O)Nc2nc(Br)ccc2C)C(=O)Cn2nc(C(C)=O)c3cc(ccc23)-c2cnc(C)nc2)CC1

InChI Key InChIKey=YSQDCVNCSQQOAW-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 511719   

TargetComplement factor D(Human)
Achillion Pharmaceuticals

US Patent
LigandPNGBDBM511719(US11084800, Cpd No. 24 | (3S)-2-(2-(3-acetyl-5-(2-...)
Affinity DataIC50: 1.00E+3nMAssay Description:Human Factor D (purified from human serum, Complement Technology, Inc.) at 80 nM final concentration is incubated with test compound at various conce...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/23/2022
Entry Details
US Patent

TargetComplement factor D(Human)
Achillion Pharmaceuticals

US Patent
LigandPNGBDBM511719(US11084800, Cpd No. 24 | (3S)-2-(2-(3-acetyl-5-(2-...)
Affinity DataIC50: 1.00E+3nMAssay Description:Human Factor D (purified from human serum, Complement Technology, Inc.) at 80 nM final concentration is incubated with test compound at various conce...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2023
Entry Details
US Patent