BDBM511738 (1R,3S,5R)-5-(acetamidomethyl)-2-(2-(3- acetyl-5-(2-methylpyrimidin-5-yl)-1H- indazol-1-yl)acetyl)-N-(6-bromopyridin-2-yl)- 2-azabicyclo[3.1.0]hexane-3-carboxamide::US11084800, Cpd No. 44::US11708351, Compound 44

SMILES CC(=O)NC[C@]12C[C@H]1N([C@@H](C2)C(=O)Nc1cccc(Br)n1)C(=O)Cn1nc(C(C)=O)c2cc(ccc12)-c1cnc(C)nc1

InChI Key InChIKey=UNIWPUAHWDDAIU-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 511738   

TargetComplement factor D(Human)
Achillion Pharmaceuticals

US Patent
LigandPNGBDBM511738(US11084800, Cpd No. 44 | (1R,3S,5R)-5-(acetamidome...)
Affinity DataIC50: 1.00E+3nMAssay Description:Human Factor D (purified from human serum, Complement Technology, Inc.) at 80 nM final concentration is incubated with test compound at various conce...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2023
Entry Details
US Patent

TargetComplement factor D(Human)
Achillion Pharmaceuticals

US Patent
LigandPNGBDBM511738(US11084800, Cpd No. 44 | (1R,3S,5R)-5-(acetamidome...)
Affinity DataIC50: 1.00E+3nMAssay Description:Human Factor D (purified from human serum, Complement Technology, Inc.) at 80 nM final concentration is incubated with test compound at various conce...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/23/2022
Entry Details
US Patent