BDBM511757 (1S,3S,5S)-5-(2-azaspiro[3.3]heptan-2- ylmethyl)-2-(2-(3-acetyl-5-(2- methylpyrimidin-5-yl)-1H-methylpyridin-2- yl)-2-azabicyclo[3.1.0]hexane-3-carboxamide::US11084800, Cpd No. 68::US11708351, Compound 68

SMILES CC(=O)c1nn(CC(=O)N2[C@H]3C[C@@]3(CN3CC4(CCC4)C3)C[C@H]2C(=O)Nc2nc(Br)ccc2C)c2ccc(cc12)-c1cnc(C)nc1

InChI Key InChIKey=ADQXQROJYUUIGO-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 511757   

TargetComplement factor D(Human)
Achillion Pharmaceuticals

US Patent
LigandPNGBDBM511757(US11084800, Cpd No. 68 | (1S,3S,5S)-5-(2-azaspiro[...)
Affinity DataIC50: 1.00E+3nMAssay Description:Human Factor D (purified from human serum, Complement Technology, Inc.) at 80 nM final concentration is incubated with test compound at various conce...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2023
Entry Details
US Patent

TargetComplement factor D(Human)
Achillion Pharmaceuticals

US Patent
LigandPNGBDBM511757(US11084800, Cpd No. 68 | (1S,3S,5S)-5-(2-azaspiro[...)
Affinity DataIC50: 1.00E+3nMAssay Description:Human Factor D (purified from human serum, Complement Technology, Inc.) at 80 nM final concentration is incubated with test compound at various conce...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/23/2022
Entry Details
US Patent