BDBM512050 US11084800, Cpd No. 395::US11447465, Cmp No. T-129::US11708351, Compound 395::methyl 3-acetyl-1-(2- ((1R,3S,5R)-3-((6- bromo-3- methylpyridin-2- yl)carbamoyl)-5- methyl-2- azabicyclo[3.1.0]hexan- 2-yl)-2-oxoethyl)-5- (2-methylpyrimidin-5- yl)-1H-indazole-6- carboxylate

SMILES COC(=O)c1cc2n(CC(=O)N3[C@@H]4C[C@]4(C)C[C@H]3C(=O)Nc3nc(Br)ccc3C)nc(C(C)=O)c2cc1-c1cnc(C)nc1

InChI Key InChIKey=OMDSWKNCXGBSMD-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 512050   

TargetComplement factor D(Human)
Achillion Pharmaceuticals

US Patent
LigandPNGBDBM512050(US11084800, Cpd No. 395 | methyl 3-acetyl-1-(2- ((...)
Affinity DataIC50: 1.00E+3nMAssay Description:Human Factor D (purified from human serum, Complement Technology, Inc.) at 80 nM final concentration is incubated with test compound at various conce...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2022
Entry Details
US Patent

TargetComplement factor D(Human)
Achillion Pharmaceuticals

US Patent
LigandPNGBDBM512050(US11084800, Cpd No. 395 | methyl 3-acetyl-1-(2- ((...)
Affinity DataIC50: 1.00E+3nMAssay Description:Human Factor D (purified from human serum, Complement Technology, Inc.) at 80 nM final concentration is incubated with test compound at various conce...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2023
Entry Details
US Patent

TargetComplement factor D(Human)
Achillion Pharmaceuticals

US Patent
LigandPNGBDBM512050(US11084800, Cpd No. 395 | methyl 3-acetyl-1-(2- ((...)
Affinity DataIC50: 1.00E+3nMAssay Description:Human Factor D (purified from human serum, Complement Technology, Inc.) at 80 nM final concentration is incubated with test compound at various conce...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/23/2022
Entry Details
US Patent

TargetComplement factor D(Human)
Achillion Pharmaceuticals

US Patent
LigandPNGBDBM512050(US11084800, Cpd No. 395 | methyl 3-acetyl-1-(2- ((...)
Affinity DataIC50: 1.00E+3nMAssay Description:Human Factor D (purified from human serum, Complement Technology, Inc.) at 80 nM final concentration is incubated with test compound at various conce...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2022
Entry Details
US Patent