BDBM5121 3-methyl-2-[(3-nitrobenzene)sulfonamido]-5-(propan-2-yl)-2,3-dihydro-1,3-thiazole-4-carboxamide::4- and 5-substituted thiazolidene deriv. 19::5-Isopropyl-3-methyl-2-{[(3-nitrophenyl)sulfonyl]imino}-2,3-dihydro-1,3-thiazole-4-carboxamide

SMILES CC(C)c1s\c(=N/S(=O)(=O)c2cccc(c2)[N+]([O-])=O)n(C)c1C(N)=O

InChI Key InChIKey=GHFIJZDKYNCSQG-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 5121   

TargetGag-Pol polyprotein [588-1127,Y768C]/[588-1147,Y768C](Human immunodeficiency virus type 1)
Yamanouchi Pharmaceutical

LigandPNGBDBM5121(5-Isopropyl-3-methyl-2-{[(3-nitrophenyl)sulfonyl]i...)
Affinity DataIC50: 2.50E+4nMAssay Description:The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro.More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/19/2005
Entry Details Article
PubMed
TargetGag-Pol polyprotein [588-1027]/[588-1147](Human immunodeficiency virus type 1)
Yamanouchi Pharmaceutical

LigandPNGBDBM5121(5-Isopropyl-3-methyl-2-{[(3-nitrophenyl)sulfonyl]i...)
Affinity DataIC50: 3.90E+4nMAssay Description:The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro.More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/19/2005
Entry Details Article
PubMed
TargetGag-Pol polyprotein [588-1027,K690N]/[588-1147,K690N](Human immunodeficiency virus type 1)
Yamanouchi Pharmaceutical

LigandPNGBDBM5121(5-Isopropyl-3-methyl-2-{[(3-nitrophenyl)sulfonyl]i...)
Affinity DataIC50: 5.00E+4nMAssay Description:The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro.More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/19/2005
Entry Details Article
PubMed