BDBM512591 acs.jmedchem.1c00409_ST.184

SMILES CC(C)C[C@H](NC(=O)OC1CCC(F)(F)CC1)C(=O)N[C@@H](C[C@@H]1CCNC1=O)C=O

InChI Key InChIKey=PHUZMTSQHVZDOX-UHFFFAOYSA-N

Data  2 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 512591   

TargetOrf1a protein(MERS-CoV)
Kansas State University Research Foundation; Wichita State University; University of Iowa Research Foundation

US Patent
LigandChemical structure of BindingDB Monomer ID 512591BDBM512591(acs.jmedchem.1c00409_ST.184 | US12583820, Compound...)
Affinity DataIC50: 70nMAssay Description:This example demonstrates the ability of the compounds of the disclosure to degrade a Nano luciferase-BRO9 fusion protein in a cell-based degradation...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/3/2026
Entry Details
US Patent

TargetReplicase polyprotein 1ab(2019-nCoV)
Michigan State University

LigandChemical structure of BindingDB Monomer ID 512591BDBM512591(acs.jmedchem.1c00409_ST.184 | US12583820, Compound...)
Affinity DataIC50: 430nMAssay Description:This is a review article. Please point to the original journal.More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/27/2022
Entry Details Article
PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
Michigan State University

LigandChemical structure of BindingDB Monomer ID 512591BDBM512591(acs.jmedchem.1c00409_ST.184 | US12583820, Compound...)
Affinity DataEC50:  900nMAssay Description:This is a review article. Please point to the original journal.More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/27/2022
Entry Details Article
PubMed
TargetOrf1a protein(MERS-CoV)
Kansas State University Research Foundation; Wichita State University; University of Iowa Research Foundation

US Patent
LigandChemical structure of BindingDB Monomer ID 512591BDBM512591(acs.jmedchem.1c00409_ST.184 | US12583820, Compound...)
Affinity DataIC50: 1.50E+3nMAssay Description:This example demonstrates the ability of the compounds of the disclosure to degrade a Nano luciferase-BRO9 fusion protein in a cell-based degradation...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/3/2026
Entry Details
US Patent

TargetReplicase polyprotein 1a(2019-nCoV)
Kansas State University Research Foundation; Wichita State University; University of Iowa Research Foundation

US Patent
LigandChemical structure of BindingDB Monomer ID 512591BDBM512591(acs.jmedchem.1c00409_ST.184 | US12583820, Compound...)
Affinity DataIC50: 1.50E+3nMAssay Description:This example demonstrates the ability of the compounds of the disclosure to degrade a Nano luciferase-BRO9 fusion protein in a cell-based degradation...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/3/2026
Entry Details
US Patent

TargetReplicase polyprotein 1ab(SARS-CoV)
Kansas State University Research Foundation; Wichita State University; University of Iowa Research Foundation

US Patent
LigandChemical structure of BindingDB Monomer ID 512591BDBM512591(acs.jmedchem.1c00409_ST.184 | US12583820, Compound...)
Affinity DataIC50: 2.30E+3nMAssay Description:This example demonstrates the ability of the compounds of the disclosure to degrade a Nano luciferase-BRO9 fusion protein in a cell-based degradation...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/3/2026
Entry Details
US Patent

TargetReplicase polyprotein 1ab(SARS-CoV)
Kansas State University Research Foundation; Wichita State University; University of Iowa Research Foundation

US Patent
LigandChemical structure of BindingDB Monomer ID 512591BDBM512591(acs.jmedchem.1c00409_ST.184 | US12583820, Compound...)
Affinity DataIC50: 2.30E+3nMAssay Description:This is a review article. Please point to the original journal.More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/27/2022
Entry Details Article
PubMed