BDBM512592 acs.jmedchem.1c00409_ST.185

SMILES Clc1ccc(cc1)C(=O)Oc1cncc(Cl)c1

InChI Key InChIKey=KLXHMZDATSPDMW-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 512592   

TargetReplicase polyprotein 1ab(2019-nCoV)
University of Bonn

Curated by ChEMBL
LigandPNGBDBM512592(acs.jmedchem.1c00409_ST.185)
Affinity DataIC50: 218nMAssay Description:Inhibition of full-length SARS CoV-2 MPro expressed in Escherichia coli BL21(DE3) using Boc-Abu-Tle-Leu-Gln-AMC as substrate incubated for 10 mins by...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetReplicase polyprotein 1ab(SARS-CoV)
Michigan State University

LigandPNGBDBM512592(acs.jmedchem.1c00409_ST.185)
Affinity DataIC50: 434nMAssay Description:This is a review article. Please point to the original journal.More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/27/2022
Entry Details Article
PubMed