BDBM515191 US11098058, Example 58::US11098058, Example 72

SMILES OCC1(CC1)C(=O)c1nc2[C@@H](F)C[C@@H](c3ccccc3)n2n1

InChI Key InChIKey=RJMNJOUSAXSSBN-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 515191   

LigandPNGBDBM515191(US11098058, Example 72 | US11098058, Example 58)
Affinity DataKi:  4.90nMAssay Description:The ability of the receptor interacting protein kinase (RIPK1) to catalyze the hydrolysis of adenosine-5′-triphosphate (ATP) is monitored using...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2022
Entry Details
US Patent

LigandPNGBDBM515191(US11098058, Example 72 | US11098058, Example 58)
Affinity DataKi:  28.7nMAssay Description:The ability of the receptor interacting protein kinase (RIPK1) to catalyze the hydrolysis of adenosine-5′-triphosphate (ATP) is monitored using...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2022
Entry Details
US Patent