BDBM515741 US11053219, Example 145::US11731956, Example 145

SMILES COc1c(Nc2cc(Nc3cc(C)c(F)cn3)ncc2C(=O)C2CC2)cccc1-c1ncn(C)n1

InChI Key InChIKey=TXTVZOQENIMDBI-UHFFFAOYSA-N

Data  2 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 515741   

TargetNon-receptor tyrosine-protein kinase TYK2(Human)
Alumis

US Patent
LigandPNGBDBM515741(US11053219, Example 145 | US11731956, Example 145 ...)
Affinity DataKd: <1nMAssay Description:Developed by DiscoverX, KINOMEscan employs proprietary active-site dependent competition binding assays to determine how compounds bind to kinases. K...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/26/2023
Entry Details
US Patent

LigandPNGBDBM515741(US11053219, Example 145 | US11731956, Example 145 ...)
Affinity DataKd: <1nMAssay Description:Streptavidin-coated magnetic beads were treated with biotinylated small molecule ligands for 30 minutes at room temperature to generate affinity resi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/23/2025
Entry Details
US Patent

TargetNon-receptor tyrosine-protein kinase TYK2(Human)
Alumis

US Patent
LigandPNGBDBM515741(US11053219, Example 145 | US11731956, Example 145 ...)
Affinity DataKd: <1nMAssay Description:DiscoverX's KINOMEscan™ is a popular platform for kinase profiling, frequently used in academic and industry witnessed by publications, ther...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/13/2022
Entry Details
US Patent