BDBM515862 US11053225, Compound 164

SMILES COc1cc(Nc2ncc(-c3cnn(c3)C(C)C)c(Nc3ccc4CCNCc4c3)n2)cc(c1)C(F)(F)F

InChI Key InChIKey=PMCFVEARPWIGJR-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 515862   

TargetTyrosine-protein kinase receptor TYRO3(Human)
Korea Research Institute of Chemical Technology

US Patent
LigandPNGBDBM515862(US11053225, Compound 164)
Affinity DataIC50: 1.40nMAssay Description:For evaluation of inhibitory activities of the compounds according to the present invention on Tyro 3, Axl, and Mer, the following test was carried o...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/13/2022
Entry Details
US Patent

TargetTyrosine-protein kinase Mer(Human)
Korea Research Institute of Chemical Technology

US Patent
LigandPNGBDBM515862(US11053225, Compound 164)
Affinity DataIC50: 640nMAssay Description:For evaluation of inhibitory activities of the compounds according to the present invention on Tyro 3, Axl, and Mer, the following test was carried o...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/13/2022
Entry Details
US Patent

TargetTyrosine-protein kinase receptor UFO(Human)
Korea Research Institute of Chemical Technology

US Patent
LigandPNGBDBM515862(US11053225, Compound 164)
Affinity DataIC50: 3.56E+3nMAssay Description:For evaluation of inhibitory activities of the compounds according to the present invention on Tyro 3, Axl, and Mer, the following test was carried o...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/13/2022
Entry Details
US Patent