BDBM516549 (2S)-1-[(2R)-2phenyl-2- (piperidin-1-yl)acetyl]-N-(4-{5- [({(2S)-1-[(2R)-2-phenyl-2- (piperidin-1-yl)acetyl]pyrrolidin- 2-yl}carbonyl)amino]-1H-indol- 2-yl}phenyl)pyrrolidine-2- carboxamide::US11053243, Example 60

SMILES O=C(Nc1ccc(cc1)-c1cc2cc(NC(=O)[C@@H]3CCCN3C(=O)[C@H](N3CCCCC3)c3ccccc3)ccc2[nH]1)[C@@H]1CCCN1C(=O)[C@H](N1CCCCC1)c1ccccc1

InChI Key InChIKey=ALOOORKLRZMRJL-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 516549   

TargetGenome polyprotein(HCV)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM516549(US11053243, Example 60 | (2S)-1-[(2R)-2phenyl-2- (...)
Affinity DataEC50:  0.130nMAssay Description:Measurement of inhibition by compounds was performed using the HCV replicon system. Several different replicons encoding different HCV genotypes or m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/13/2022
Entry Details
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