BDBM516893 US11104665, ACS Med. Chem. Lett. 2017, 8, 1252-1257 Example 19
SMILES FC(F)(F)c1cc(COC(=O)N2C[C@H]3C(CNC(=O)c4ccc5n[nH]nc5c4)[C@H]3C2)cc(c1)C(F)(F)F
InChI Key InChIKey=ZDOBSAPHUUUOHX-ALOPSCKCSA-N
Data 1 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 1 hit for monomerid = 516893
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 2(Homo sapiens (Human))
Boehringer Ingelheim International
US Patent
Boehringer Ingelheim International
US Patent
Affinity DataIC50: 2.20nMAssay Description:5 nM recombinant ATX (Cayman Chemicals) was supplemented to 50 mM Tris buffer (pH 8.0) containing 3 mM KCl, 1 mM CaCl2, 1 mM MgCl2 0.14 mM NaCl, and ...More data for this Ligand-Target Pair