BDBM517132 6-benzyl-5-(cyclohexylmethyl)-1- tetrahydropyran-4-yl-pyrazolo[3,4- d]pyrimidin-4-one::US11104680, Example 1

SMILES O=c1n(CC2CCCCC2)c(Cc2ccccc2)nc2n(ncc12)C1CCOCC1

InChI Key InChIKey=YXOLEIZBMQWRJW-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 517132   

LigandPNGBDBM517132(US11104680, Example 1 | 6-benzyl-5-(cyclohexylmeth...)
Affinity DataIC50: 120nMAssay Description:PDE1A, PDE1B and PDE1C assays were performed as follows: the assays was performed in 60 μL samples containing a fixed amount of the PDE1 enzyme ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/13/2022
Entry Details
US Patent

LigandPNGBDBM517132(US11104680, Example 1 | 6-benzyl-5-(cyclohexylmeth...)
Affinity DataIC50: 320nMAssay Description:PDE1A, PDE1B and PDE1C assays were performed as follows: the assays was performed in 60 μL samples containing a fixed amount of the PDE1 enzyme ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/13/2022
Entry Details
US Patent

LigandPNGBDBM517132(US11104680, Example 1 | 6-benzyl-5-(cyclohexylmeth...)
Affinity DataIC50: 349nMAssay Description:PDE1A, PDE1B and PDE1C assays were performed as follows: the assays was performed in 60 μL samples containing a fixed amount of the PDE1 enzyme ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/13/2022
Entry Details
US Patent