BDBM517133 5-(4-methoxybenzyl)-6-methyl-1- (tetrahydro-2H-pyran-4-yl)-1H- pyrazolo[3,4-d]pyrimidin-4(5H)-one::US11104680, Example 2

SMILES COc1ccc(Cn2c(C)nc3n(ncc3c2=O)C2CCOCC2)cc1

InChI Key InChIKey=IAAHGVIRZIKPHA-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 517133   

LigandPNGBDBM517133(US11104680, Example 2 | 5-(4-methoxybenzyl)-6-meth...)
Affinity DataIC50: 62nMAssay Description:PDE1A, PDE1B and PDE1C assays were performed as follows: the assays was performed in 60 μL samples containing a fixed amount of the PDE1 enzyme ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/13/2022
Entry Details
US Patent

LigandPNGBDBM517133(US11104680, Example 2 | 5-(4-methoxybenzyl)-6-meth...)
Affinity DataIC50: 74nMAssay Description:PDE1A, PDE1B and PDE1C assays were performed as follows: the assays was performed in 60 μL samples containing a fixed amount of the PDE1 enzyme ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/13/2022
Entry Details
US Patent

LigandPNGBDBM517133(US11104680, Example 2 | 5-(4-methoxybenzyl)-6-meth...)
Affinity DataIC50: 132nMAssay Description:PDE1A, PDE1B and PDE1C assays were performed as follows: the assays was performed in 60 μL samples containing a fixed amount of the PDE1 enzyme ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/13/2022
Entry Details
US Patent