BDBM517137 6-ethyl-5-[(4-methoxyphenyl)methyl]- 1-tetrahydropyran-4-yl-pyrazolo[3,4- d]pyrimidin-4-one::US11104680, Example 6

SMILES CCc1nc2n(ncc2c(=O)n1Cc1ccc(OC)cc1)C1CCOCC1

InChI Key InChIKey=KVMXASWJIZJMBZ-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 517137   

LigandPNGBDBM517137(US11104680, Example 6 | 6-ethyl-5-[(4-methoxypheny...)
Affinity DataIC50: 80nMAssay Description:PDE1A, PDE1B and PDE1C assays were performed as follows: the assays was performed in 60 μL samples containing a fixed amount of the PDE1 enzyme ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/13/2022
Entry Details
US Patent

LigandPNGBDBM517137(US11104680, Example 6 | 6-ethyl-5-[(4-methoxypheny...)
Affinity DataIC50: 107nMAssay Description:PDE1A, PDE1B and PDE1C assays were performed as follows: the assays was performed in 60 μL samples containing a fixed amount of the PDE1 enzyme ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/13/2022
Entry Details
US Patent

LigandPNGBDBM517137(US11104680, Example 6 | 6-ethyl-5-[(4-methoxypheny...)
Affinity DataIC50: 140nMAssay Description:PDE1A, PDE1B and PDE1C assays were performed as follows: the assays was performed in 60 μL samples containing a fixed amount of the PDE1 enzyme ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/13/2022
Entry Details
US Patent