BDBM517138 6-(methoxymethyl)-5-[(4- methoxyphenyl)methyl]-1- tetrahydropyran-4-yl-pyrazolo[3,4- d]pyrimidin-4-one::US11104680, Example 7

SMILES COCc1nc2n(ncc2c(=O)n1Cc1ccc(OC)cc1)C1CCOCC1

InChI Key InChIKey=MZDJCPNZHVQURG-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 517138   

LigandPNGBDBM517138(US11104680, Example 7 | 6-(methoxymethyl)-5-[(4- m...)
Affinity DataIC50: 181nMAssay Description:PDE1A, PDE1B and PDE1C assays were performed as follows: the assays was performed in 60 μL samples containing a fixed amount of the PDE1 enzyme ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/13/2022
Entry Details
US Patent

LigandPNGBDBM517138(US11104680, Example 7 | 6-(methoxymethyl)-5-[(4- m...)
Affinity DataIC50: 325nMAssay Description:PDE1A, PDE1B and PDE1C assays were performed as follows: the assays was performed in 60 μL samples containing a fixed amount of the PDE1 enzyme ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/13/2022
Entry Details
US Patent

LigandPNGBDBM517138(US11104680, Example 7 | 6-(methoxymethyl)-5-[(4- m...)
Affinity DataIC50: 345nMAssay Description:PDE1A, PDE1B and PDE1C assays were performed as follows: the assays was performed in 60 μL samples containing a fixed amount of the PDE1 enzyme ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/13/2022
Entry Details
US Patent